Enhancing gene expression and safety through specialized techniques, including optimization of hairpins, palindromes, CpG islands, cryptic polyA sites, and more.

shRNA design process combines rigorous standards with detailed reporting to deliver high-efficiency gene targeting with minimized off-target effects.

gRNA design for CRISPR-Cas9 is precise, efficient, and specific, with eliminated off-target effects at the PAM end.

miRNA-based shRNA services ensure precise gene silencing, reduce off-target effects, and minimize cellular toxicity.

29,000 miRNAs from 181 species.

Loop sequences and statistics from 181 species.

siRNA databases for 23,000 human genes and 21,000 mouse genes

1,634 specific promoter candidates corresponding to 78 different cell types