DNA OPTIMIZATION


RNABASE specializes in optimizing genetic sequences, ensuring enhanced functionality, increased expression levels, and improved safety across various biological applications.

[1] DNA

  • DNA hairpin
  • Palindromic sequences
  • CpG islands
  • Cryptic polyA

[2] RNA

  • Secondary Structure - Predicting RNA secondary structures, providing valuable insights into their folding patterns.
  • Minimum Free Energy - Optimizing RNAs to reduce their minimum free energy, resulting in increased RNA expression levels.

[3] AAV

  • Recognization - Identifying AAV-specific sequences ITR (Inverted Terminal Repeat), visualizing ITR, predicting the yield of AAV packaging.
  • Optimization - Optimizing elements to enhance production yield.

[4] mRNA

  • Optimization - Optimizing mRNA 5'UTR, 3'UTR, and polyA tails to increase mRNA stability.