At RNABase, we specialize in optimizing genetic sequences, ensuring enhanced functionality, increased expression levels, and improved safety across various biological applications.

1. DNA OPTIMIZATION

* DNA hairpin

* Palindromic sequences

* CpG islands

* Cryptic polyA

2. RNA OPTIMIZATION

* Secondary Structure - Predicting RNA secondary structures, providing valuable insights into their folding patterns.

* Minimum Free Energy - Optimizing RNAs to reduce their minimum free energy, resulting in increased RNA expression levels.

3. VIRUS ELEMENTS

* Recognization - Identifying virus-specific sequences like ITR (Inverted Terminal Repeat) and LTR (Long Terminal Repeat), predicting the yield of virus packaging.

* Optimization - Optimizing elements to enhance production yield.

4. MESSAGE RNA (mRNA)

* Optimization - Optimizing mRNA 5'UTR, 3'UTR and polyA tails to increase mRNA stability.